| Rank | Total Population ▼ | School District / Population |
| 1. | 147,771 | Sioux Falls School District 49-5 / 147,771 |
| 2. | 95,347 | Rapid City School District 51-4 / 95,347 |
| 3. | 31,829 | Aberdeen School District 06-1 / 31,829 |
| 4. | 25,969 | Brookings School District 05-1 / 25,969 |
| 5. | 25,208 | Watertown School District 14-4 / 25,208 |
| 6. | 20,147 | Yankton School District 63-3 / 20,147 |
| 7. | 18,378 | Mitchell School District 17-2 / 18,378 |
| 8. | 18,360 | Harrisburg School District 41-2 / 18,360 |
| 9. | 18,255 | Meade School District 46-1 / 18,255 |
| 10. | 16,837 | Brandon Valley School District 49-2 / 16,837 |
| 11. | 16,279 | Pierre School District 32-2 / 16,279 |
| 12. | 15,757 | Spearfish School District 40-2 / 15,757 |
| 13. | 15,635 | Huron School District 02-2 / 15,635 |
| 14. | 14,005 | Shannon County School District 65-1 / 14,005 |
| 15. | 12,343 | Vermillion School District 13-1 / 12,343 |
| 16. | 11,934 | Douglas School District 51-1 / 11,934 |
| 17. | 9,859 | Todd County School District 66-1 / 9,859 |
| 18. | 9,408 | Madison Central School District 39-2 / 9,408 |
| 19. | 8,032 | Custer School District 16-1 / 8,032 |
| 20. | 8,009 | Sisseton School District 54-2 / 8,009 |
| 21. | 7,771 | Belle Fourche School District 09-1 / 7,771 |
| 22. | 6,876 | Lead-Deadwood School District 40-1 / 6,876 |
| 23. | 6,850 | Tea Area School District 41-5 / 6,850 |
| 24. | 6,452 | Chamberlain School District 07-1 / 6,452 |
| 25. | 6,415 | West Central School District 49-7 / 6,415 |
| 26. | 6,327 | Dakota Valley School District 61-8 / 6,327 |
| 27. | 6,080 | Lennox School District 41-4 / 6,080 |
| 28. | 5,738 | Hot Springs School District 23-2 / 5,738 |
| 29. | 5,587 | Tri-Valley School District 49-6 / 5,587 |
| 30. | 5,501 | Dell Rapids School District 49-3 / 5,501 |
| 31. | 5,487 | Canton School District 41-1 / 5,487 |
| 32. | 5,453 | Milbank School District 25-4 / 5,453 |
| 33. | 5,056 | Eagle Butte School District 20-1 / 5,056 |
| 34. | 4,687 | Bon Homme School District 04-2 / 4,687 |
| 35. | 4,528 | Winner School District 59-2 / 4,528 |
| 36. | 4,254 | Elk Point-Jefferson School District 61-7 / 4,254 |
| 37. | 4,132 | Mobridge-Pollock School District 62-6 / 4,132 |
| 38. | 4,078 | Wagner School District 11-4 / 4,078 |
| 39. | 3,790 | Sioux Valley School District 05-5 / 3,790 |
| 40. | 3,704 | Groton Area School District 06-6 / 3,704 |
| 41. | 3,637 | Beresford School District 61-2 / 3,637 |
| 42. | 3,601 | Redfield School District 56-4 / 3,601 |
| 43. | 3,583 | Flandreau School District 50-3 / 3,583 |
| 44. | 3,493 | Kadoka School District 35-2 / 3,493 |
| 45. | 3,440 | Bennett County School District 03-1 / 3,440 |
| 46. | 3,312 | Webster School District 18-4 / 3,312 |
| 47. | 3,256 | Deuel School District 19-4 / 3,256 |
| 48. | 3,147 | Hamlin School District 28-3 / 3,147 |
| 49. | 3,146 | Hill City School District 51-2 / 3,146 |
| 50. | 3,112 | Platte-Geddes School District 11-5 / 3,112 |
| 51. | 3,096 | Parkston School District 33-3 / 3,096 |
| 52. | 3,036 | Miller Area School District 29-4 / 3,036 |
| 53. | 3,033 | Lyman School District 42-1 / 3,033 |
| 54. | 2,984 | Stanley County School District 57-1 / 2,984 |
| 55. | 2,883 | Britton-Hecla School District 45-4 / 2,883 |
| 56. | 2,782 | McLaughlin School District 15-2 / 2,782 |
| 57. | 2,633 | Garretson School District 49-4 / 2,633 |
| 58. | 2,583 | Freeman School District 33-1 / 2,583 |
| 59. | 2,566 | Newell School District 09-2 / 2,566 |
| 60. | 2,401 | Alcester-Hudson School District 61-1 / 2,401 |
| 61. | 2,390 | Irene-Wakonda School District 13-3 / 2,390 |
| 62. | 2,366 | McCook Central School District 43-7 / 2,366 |
| 63. | 2,354 | Clark School District 12-2 / 2,354 |
| 64. | 2,349 | Viborg School District 60-5 / 2,349 |
| 65. | 2,345 | Ipswich School District 22-6 / 2,345 |
| 66. | 2,314 | Howard School District 48-3 / 2,314 |
| 67. | 2,162 | Lemmon School District 52-4 / 2,162 |
| 68. | 2,148 | Gregory School District 26-4 / 2,148 |
| 69. | 2,104 | Andes Central School District 11-1 / 2,104 |
| 70. | 2,082 | Parker School District 60-4 / 2,082 |
| 71. | 2,065 | Agar-Blunt-Onida School District 58-3 / 2,065 |
| 72. | 2,057 | Faulkton School District 24-4 / 2,057 |
| 73. | 2,035 | Baltic School District 49-1 / 2,035 |
| 74. | 1,956 | Highmore-Harrold School District 34-2 / 1,956 |
| 75. | 1,948 | Hanson School District 30-1 / 1,948 |
| 76. | 1,941 | Deubrook School District 05-6 / 1,941 |
| 77. | 1,914 | Colman-Egan School District 50-5 / 1,914 |
| 78. | 1,871 | Dupree School District 64-2 / 1,871 |
| 79. | 1,845 | Northwestern Area School District 56-7 / 1,845 |
| 80. | 1,842 | Scotland School District 04-3 / 1,842 |
| 81. | 1,833 | Arlington School District 38-1 / 1,833 |
| 82. | 1,805 | White River School District 47-1 / 1,805 |
| 82. | 1,805 | Haakon School District 27-1 / 1,805 |
| 84. | 1,773 | Selby School District 62-5 / 1,773 |
| 85. | 1,762 | Wessington Springs School District 36-2 / 1,762 |
| 86. | 1,759 | Emery School District 30-2 / 1,759 |
| 87. | 1,748 | Estelline School District 28-2 / 1,748 |
| 88. | 1,723 | Wall School District 51-5 / 1,723 |
| 89. | 1,713 | Chester School District 39-1 / 1,713 |
| 90. | 1,710 | De Smet School District 38-2 / 1,710 |
| 91. | 1,609 | Wilmot School District 54-7 / 1,609 |
| 92. | 1,523 | Wolsey-Wessington School District 02-6 / 1,523 |
| 92. | 1,523 | Langford School District 45-2 / 1,523 |
| 94. | 1,469 | Tripp-Delmont School District 33-5 / 1,469 |
| 95. | 1,455 | Timber Lake School District 20-3 / 1,455 |
| 96. | 1,436 | Centerville School District 60-1 / 1,436 |
| 97. | 1,434 | Gettysburg School District 53-1 / 1,434 |
| 98. | 1,401 | Marion School District 60-3 / 1,401 |
| 99. | 1,353 | Burke School District 26-2 / 1,353 |
| 100. | 1,335 | Castlewood School District 28-1 / 1,335 |
| 101. | 1,320 | Menno School District 33-2 / 1,320 |
| 102. | 1,315 | Waubay School District 18-3 / 1,315 |
| 103. | 1,293 | Elkton School District 05-3 / 1,293 |
| 104. | 1,279 | Eureka School District 44-1 / 1,279 |
| 105. | 1,263 | Avon School District 04-1 / 1,263 |
| 105. | 1,263 | Harding County School District 31-1 / 1,263 |
| 107. | 1,252 | Corsica School District 21-2 / 1,252 |
| 108. | 1,248 | Willow Lake School District 12-3 / 1,248 |
| 109. | 1,238 | Plankinton School District 01-1 / 1,238 |
| 110. | 1,233 | Sanborn Central School District 55-5 / 1,233 |
| 111. | 1,229 | Colome Consolidated School District 59-3 / 1,229 |
| 112. | 1,223 | Edgemont School District 23-1 / 1,223 |
| 113. | 1,217 | Lake Preston School District 38-3 / 1,217 |
| 114. | 1,213 | Rosholt School District 54-4 / 1,213 |
| 115. | 1,208 | New Underwood School District 51-3 / 1,208 |
| 116. | 1,204 | Armour School District 21-1 / 1,204 |
| 117. | 1,194 | Leola School District 44-2 / 1,194 |
| 118. | 1,189 | Woonsocket School District 55-4 / 1,189 |
| 119. | 1,167 | Montrose School District 43-2 / 1,167 |
| 120. | 1,165 | Hitchcock-Tulare School District 56-6 / 1,165 |
| 121. | 1,138 | Edmunds Central School District 22-5 / 1,138 |
| 122. | 1,122 | Warner School District 06-5 / 1,122 |
| 123. | 1,118 | Iroquois School District 02-3 / 1,118 |
| 124. | 1,102 | Waverly School District 14-5 / 1,102 |
| 125. | 1,092 | Frederick Area School District 06-2 / 1,092 |
| 126. | 1,051 | Kimball School District 07-2 / 1,051 |
| 127. | 1,048 | Mount Vernon School District 17-3 / 1,048 |
| 128. | 1,047 | Canistota School District 43-1 / 1,047 |
| 129. | 987 | Florence School District 14-1 / 987 |
| 130. | 981 | Hoven School District 53-2 / 981 |
| 131. | 978 | Doland School District 56-2 / 978 |
| 132. | 929 | Grant-Deuel School District 25-3 / 929 |
| 132. | 929 | Ethan School District 17-1 / 929 |
| 134. | 907 | South Central School District 26-5 / 907 |
| 135. | 881 | Gayville-Volin School District 63-1 / 881 |
| 136. | 873 | Big Stone City School District 25-1 / 873 |
| 137. | 849 | Stickney School District 01-2 / 849 |
| 138. | 831 | Oldham-Ramona School District 39-5 / 831 |
| 139. | 829 | Bison School District 52-1 / 829 |
| 140. | 806 | Faith School District 46-2 / 806 |
| 141. | 779 | Jones County School District 37-3 / 779 |
| 142. | 737 | Herreid School District 10-1 / 737 |
| 143. | 736 | McIntosh School District 15-1 / 736 |
| 144. | 732 | Bowdle School District 22-1 / 732 |
| 145. | 686 | White Lake School District 01-3 / 686 |
| 146. | 621 | Summit School District 54-6 / 621 |
| 147. | 609 | Henry School District 14-2 / 609 |
| 148. | 534 | Rutland School District 39-4 / 534 |
| 149. | 363 | Oelrichs School District 23-3 / 363 |
| 150. | 332 | Smee School District 15-3 / 332 |
| 151. | 259 | Elk Mountain School District 16-2 / 259 |
Please note that we only rank locations with 'Total Population' data. The rank above might not be a complete list. Locations without 'Total Population' data are not listed.
